Management in Health, Vol 16, No 1 (2012)

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NEUROBLASTOMA IN ROMANIA, WHERE WE STAND AND WHAT SHOULD WE DO

M.C. POPOIU, V.L. DAVID, E. BOERIU, A.V. POPOIU, S. ARGHIRESCU, C. VLADESCU, N.D. CHIRIAC, I. MUSAT, E.S. BOIA

Abstract


Neuroblastoma (NB) is the most common solid extra-cranial malignancy of childhood and is responsible for approximately 15% of all pediatric cancer deaths.

AIM: The purpose of this report is to provide and analyze specific epidemiologic data regarding the frequency, demographics, age and stage of the disease at diagnostic, treatment methods and outcomes of the treatment of NB in Romania over a 3 years period.

MATERIAL AND METHODS: In this purpose, we inquired the database of the National School of Public Health, Management and Professional Development using specific principal diagnosis codes, for NB tumors.

RESULTS: 623 cases with NB were reported in Romania in a 3 years period (2007-2009). The sex ratio of M: F 1.1: 1. In the majority of the cases (67%), the tumor origin was the adrenal gland. Only in 31 patients a surgical procedure was recorded.

CONCLUSIONS: NB is an aggressive tumor with high incidence in the 1-6 years age group and with equal sex distribution. Currently there is a high rate of hospital admission/ patient with a median hospital stay of 5 days. Only in approximately 10% of the patients, the tumor is resected, meaning a complete cure of the disease. We consider that the current medical system for diagnosis and treatment of NB must be improved and, is our believe the way for this is to concentrate the resources in fewer but more specialized medical centers for diagnosis and treatment of NB.

 

Keywords: neuroblastoma, epidemiology, treatment methods, outcomes


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